

Pain, whether acute or chronic, is an unavoidable part of our lives but greatly impacts our lifestyle. While pharmaceuticals primarily alleviate pain, noninvasive methods like music theory have started to be recognized for their effectiveness. Music's ability to modulate neurochemical processes in the brain has influenced how pain is perceived and managed, offering a holistic alternative approach to traditional pharmaceutical pain management strategies.
Pain perception is intricate and involves many different neural pathways and neurotransmitters. The human brain perceives pain through nociceptors, which help with detecting harmful stimuli and send signals through the spinal cord to the cerebral cortex, where the pain is perceived. Emotions, memories, and other stimuli like music play an important role in shaping how pain is experienced. Music can disrupt pain signaling by engaging with neurochemical systems in the brain, allowing the body to cope with discomfort.
Listening to music activates the brain's reward system, playing an important role in the release of dopamine, a neurotransmitter associated with pleasure and happiness. By activating this pathway, music creates a sense of euphoria from the dopamine release, reducing discomfort levels. Music stimulates the production of endorphins, the body's natural painkillers. These opioid-like neuropeptides bind to opioid receptors in the brain, interfering with pain signals and producing a similar effect to pharmaceutical pain relief. In addition to dopamine and endorphins, music also promotes the release of oxytocin, a hormone that reduces stress. It has been shown to increase pain tolerance; whether it be used before surgery to ease anxiety, during labor to help mothers cope with contractions, or in palliative care to improve quality of life, music is a noninvasive method of pain management. Another important neurotransmitter, serotonin, helps regulate mood and pain tolerance. Higher serotonin levels are connected to increased emotional stability and peacefulness, reducing levels of pain perception.
Multiple clinical studies have shown music's effects in alleviating pain in many different conditions. Patients who listened to music before, during, or after the procedure reported lower pain levels and needed fewer over-the-counter medications. Patients who have chronic pain conditions like fibromyalgia, arthritis, and low back pain experience improved quality of life through music theory. Pregnant women who listen to music during labor have shown lower anxiety levels. Music therapy has also been used for treatments for cancer patients, giving them a sense of relief from physical pain as well as emotional distress.
Music theory works most effectively when it is adjusted to one's individual preferences. Preferred music genres release strong dopamine and endorphin responses. Using music therapy in clinical settings shows great potential and hope for a holistic approach to pain management.
Citations: Beard, M. (2025, February 7). Listening to music with this “personal” characteristic can relieve pain. New York Post. https://nypost.com/2025/02/07/health/music-with-this-personal-characteristic-could-relieve-pain/
Arnold, C. A., Bagg, M. K., & Harvey, A. R. (2024). The psychophysiology of music-based interventions and the experience of pain. Frontiers in Psychology, 15. https://doi.org/10.3389/fpsyg.2024.1361857
https://facebook.com/GeorgeHlavaxPage. (2024, October 2). How Your Brain’s Chemistry Shapes Your Mood and How You Can Learn to Consciously Control It - humanmindinstitute.org. Human Mind Institute. https://humanmindinstitute.org/how-brain-chemistry-shapes-your-mood-and-how-to-control-it-consciously/